USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q8TCD5 USC-OGP 2-DE database:  Q8TCD5 Q8TCD5 General information about the entry View entry in simple text format Entry name NT5C_HUMAN Primary accession number Q8TCD5 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=5'(3')-deoxyribonucleotidase, cytosolic type; EC=3.1.3.-; AltName: Full=Cytosolic 5',3'-pyrimidine nucleotidase; AltName: Full=Deoxy-5'-nucleotidase 1; Short=dNT-1;. Gene name Name=NT5C Synonyms=DNT1, UMPH2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-1019: pI=5.93; Mw=24956 Cross-references UniProtKB/Swiss-Prot Q8TCD5; NT5C_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name NT5C_HUMAN Primary accession number Q8TCD5 Secondary accession number(s) Q96HS6 Q9NP82 Sequence was last modified on  October 31, 2003 (version 2) Annotations were last modified on  March 15, 2017 (version 137) Name and origin of the protein Description RecName: Full=5'(3')-deoxyribonucleotidase, cytosolic type; EC=3.1.3.-; AltName: Full=Cytosolic 5',3'-pyrimidine nucleotidase; AltName: Full=Deoxy-5'-nucleotidase 1; Short=dNT-1; Gene name Name=NT5C Synonyms=DNT1, UMPH2 Encoded on Name=NT5C; Synonyms=DNT1, UMPH2 Keywords 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Magnesium; Metal-binding; Nucleotide metabolism; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF154829; AAF36534.2; -; mRNA EMBL AK000419; BAA91151.1; -; mRNA EMBL AC022211; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC008183; AAH08183.1; -; mRNA EMBL BC017454; AAH17454.1; -; mRNA EMBL BC022334; AAH22334.1; -; mRNA EMBL BK000192; DAA00070.1; -; Genomic_DNA CCDS CCDS11715.1; -. [Q8TCD5-1]; . RefSeq NP_001239306.1; NM_001252377.1; . RefSeq NP_055410.1; NM_014595.2. [Q8TCD5-1]; . UniGene Hs.67201; -; . PDB 2I7D; X-ray; 1.20 A; A/B=3-195 PDB 4L57; X-ray; 1.08 A; A/B=1-195 PDB 4YIH; X-ray; 1.82 A; A/B=1-195 PDBsum 2I7D; -; . PDBsum 4L57; -; . PDBsum 4YIH; -; . ProteinModelPortal Q8TCD5; -; . SMR Q8TCD5; -; . BioGrid 119049; 7; . IntAct Q8TCD5; 1; . STRING 9606.ENSP00000245552; -; . DrugBank DB00709; Lamivudine; . DEPOD Q8TCD5; -; . iPTMnet Q8TCD5; -; . PhosphoSitePlus Q8TCD5; -; . BioMuta NT5C; -; . DMDM 38258193; -; . OGP Q8TCD5; -; . EPD Q8TCD5; -; . PaxDb Q8TCD5; -; . PeptideAtlas Q8TCD5; -; . PRIDE Q8TCD5; -; . DNASU 30833; -; . Ensembl ENST00000245552; ENSP00000245552; ENSG00000125458. [Q8TCD5-1]; . Ensembl ENST00000580758; ENSP00000462123; ENSG00000125458. [Q8TCD5-2]; . GeneID 30833; -; . KEGG hsa:30833; -; . UCSC uc060jte.1; human. [Q8TCD5-1]; . CTD 30833; -; . DisGeNET 30833; -; . GeneCards NT5C; -; . HGNC HGNC:17144; NT5C; . HPA HPA021581; -; . HPA HPA023632; -; . MIM 191720; gene; . neXtProt NX_Q8TCD5; -; . OpenTargets ENSG00000125458; -; . PharmGKB PA31798; -; . eggNOG ENOG410IHG0; Eukaryota; . eggNOG ENOG410XQYS; LUCA; . GeneTree ENSGT00390000011596; -; . HOGENOM HOG000236944; -; . HOVERGEN HBG045599; -; . KO K01081; -; . OMA FTCCHNR; -; . OrthoDB EOG091G0L73; -; . PhylomeDB Q8TCD5; -; . TreeFam TF331117; -; . Reactome R-HSA-73621; Pyrimidine catabolism; . Reactome R-HSA-74259; Purine catabolism; . SABIO-RK Q8TCD5; -; . EvolutionaryTrace Q8TCD5; -; . GeneWiki NT5C; -; . GenomeRNAi 30833; -; . PRO PR:Q8TCD5; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000125458; -; . CleanEx HS_NT5C; -; . ExpressionAtlas Q8TCD5; baseline and differential; . Genevisible Q8TCD5; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IEA:Ensembl; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0008253; F:5'-nucleotidase activity; EXP:Reactome; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0008252; F:nucleotidase activity; IDA:UniProtKB; . GO GO:0019103; F:pyrimidine nucleotide binding; IDA:UniProtKB; . GO GO:0016311; P:dephosphorylation; IDA:UniProtKB; . GO GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome; . GO GO:0009223; P:pyrimidine deoxyribonucleotide catabolic process; IDA:UniProtKB; . GO GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome; . Gene3D 3.40.50.1000; -; 1; . InterPro IPR010708; 5'(3')-deoxyribonucleotidase; . InterPro IPR023214; HAD-like_dom; . Pfam PF06941; NT5C; 1; . SUPFAM SSF56784; SSF56784; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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